Selected treatment-emergent Adverse Events1
Adverse Reaction
Adverse Reaction |
Minocycline Hydrochloride
Minocycline Hydrochloride Sustained-Release Tablets (1mg/kg) N = 674 Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
Placebo N = 364 |
Adverse Reaction
At least one treatment-emergent event |
Minocycline Hydrochloride
379 (56%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
197 (54%) |
Adverse Reaction
Headache |
Minocycline Hydrochloride
152 (23%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
83 (23%) |
Adverse Reaction
Fatigue |
Minocycline Hydrochloride
62 (9%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
24 (7%) |
Adverse Reaction
Dizziness |
Minocycline Hydrochloride
59 (9%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
17 (5%) |
Adverse Reaction
Pruritis |
Minocycline Hydrochloride
31 (5%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
16 (4%) |
Adverse Reaction
Malaise |
Minocycline Hydrochloride
26 (5%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
9 (3%) |
Adverse Reaction
Mood alteration |
Minocycline Hydrochloride
17 (3%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
9 (3%) |
Adverse Reaction
Somnolence |
Minocycline Hydrochloride
13 (2%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
9 (1%) |
Adverse Reaction
Urticaria |
Minocycline Hydrochloride
10 (2%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
3 (1%) |
Adverse Reaction
Tinnitus |
Minocycline Hydrochloride
10 (2%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
1 (0%) |
Adverse Reaction
Arthralgia |
Minocycline Hydrochloride
9 (1%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
1 (0%) |
Adverse Reaction
Vertigo |
Minocycline Hydrochloride
8 (1%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
1 (0%) |
Adverse Reaction
Dry Mouth |
Minocycline Hydrochloride
7 (1%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
1 (0%) |
Adverse Reaction
Myalgia |
Minocycline Hydrochloride
7 (1%) Sustained-Release Tablets (1mg/kg) N = 674 |
Placebo N = 364
1 (0%) |